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International Center for Research and Research Training in
Endocrine Disruption of
Male Reproduction and Child Health
Chair & vice-chair of LOC
April 2024
Our EDMaRC colleagues Anders Juul and Katharina Main are leading the local organizing committee for the first joint scientific congress of the European Society of Paediatric Endocrinology (ESPE) and European Society of Endocrinology (ESE) planned in Copenhagen from May 10-13, 2025. The theme of the congress is "Connecting Endocrinology across the Life Course," highlighting the importance of considering the entire life cycle for disease prevention and optimizing endocrine care.
January 2024
EDMaRC is partner in the new Research and Innovation action under the EU Horizon programme: MERLON - Merging Scientific Evidence with Regulatory Practices and Leveraging Identification of Endocrine Disruptors using New Approach Methodologies.
The project started 1. january 2024 and will last five years. The consortium is lead by Prof. Terje Svingen at Technical University of Denmark - DTU.
New grant to study psychosocial consequences of infertility
December 2023
Infertility affects 15% of all couples with a desire to become parents, and the fear of not being able to become parents can be a great burden. Thus, we are proud that EDMaRC researcher Lærke Priskorn received a grant under the Inge Lehmann programme, Independent Research Fund Denmark, to investigate the specific psychosocial consequences of infertility and which couples are at particular risk of experiencing these, allowing us to take even better care of our infertile patients in the future.
microRNAs as biomarkers of pubertal onset?
December 2023
Puberty marks the transition from childhood to adulthood and a decline in the age at pubertal onset has been observed over the past decades. No biomarkers for early detection of central puberty activation have been found so far. By receiving a grant from the Capital Region of Denmark, EDMaRC researcher Nina Mørup Nygaard has been given the opportunity to investigate microRNAs as biomarkers for pubertal onset in girls. This may give us a new method to diagnose girls with central precocious puberty.
New Publications:
The epidemiology of cryptorchidism and potential risk factors, including endocrine disrupting chemicals.
Holmboe et al. Front Endocrinol (Lausanne). 2024,15:1343887.

Growth and Adult Height Attainment in Danish Transgender Adolescents Treated with GnRH Analog and Sex Hormones.
Norup et al. J Clin Endocrinol Metab. 2024, in press

The influence of body composition on the response to dynamic stimulation of the endocrine pituitary-testis axis.
Abildgaard et al. Int J Obes. 2024, in press

Cohort profile: The Copenhagen Analgesic Study-The COPANA cohort.
Fischer et al  Paediatr Perinat Epidemiol. 2024, in press

Low-serum antimüllerian hormone is linked with poor semen quality in infertile men screened for participation in a randomized controlled trial.
Holt et al. Fertil Steril. 2024, S0015-0282(24)00193-6.

Polygenic Scores for Adult Testosterone and SHBG Levels Are Associated With Reproductive Hormone Levels in Male Infants.
Busch et al. J Clin Endocrinol Metab 2024, in press

Girls with idiopathic central precocious puberty did not display substantial changes in body mass index after treatment with gonadotropin-releasing hormone analogues.
Uldbjerg et al. Acta Paediatr 2024, in press

Is male gynaecomastia associated with an increased risk of death? A nationwide register-based cohort study
Bräuner et al. BMJ Open. 2024, 14(2):e076608

Cotinine concentrations in maternal serum and amniotic fluid during pregnancy and risk of testicular germ cell cancer in the offspring: A prospective nested case-control study.
Beck et al. Int J Cancer. 2024. 154:71-80

Ovarian Follicular Fluid Levels of Phthalates and Benzophenones in relation to Fertility Outcomes.
Beck et al. Env Int 2023, 183:108383

Time to pregnancy and life expectancy: A cohort study of 18796 pregnant couples.
Lindahl-Jacobsen et al.  Hum Reprod 2023, 39(3):595-603.

Differentiation of Idiopathic Central Precocious Puberty from Premature Thelarche using Principal Component Analysis.
Cleemann Wang  et al. J Clin Endocrinol Metab 2023,109(2):370-379.

Maternal phthalate exposure during pregnancy and testis function of young adult sons.
Henriksen et al. Sci Total Environ. 2023, 871:161914.

Sex-independent timing of the onset of central puberty revealed by nocturnal luteinizing hormone concentrations.
Demir et al. Clinical Endocrinology. 2023 99(6): 552-558.

Prenatal paraben exposures and birth size: Sex-specific associations in a healthy population - A study from the Odense Child Cohort.
Bräuner et al. 2023 Sci Total Environ. 869:161748.

Reproductive hormones, bone mineral content, body composition and testosterone therapy in boys and adolescents with Klinefelter syndrome
Krabbe et al. 2023 Endocrine Connections. 12, 7, e230031.

Reduced serum concentrations of biomarkers reflecting Leydig and Sertoli cell function in male patients with congenital adrenal hyperplasia
Johannsen et al. 2023 Endocrine Connections. 12, 8, e230073.

Testicular function is associated with cardiometabolic health markers: A cross-sectional study of 2289 young men.
Hansen et al. 2023 Andrology 11(3):561-574.

Pituitary-testis axis dysfunction following adjuvant androgen deprivation therapy
Abildgaard et al. 2023 Endocrine-Related Cancer. 30, 1, e220246.
Dept. of Growth and Reproduction
Copenhagen University Hospital, Rigshospitalet
Blegdamsvej 9
DK-2100 Copenhagen Denmark

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